* {
  margin: 0;
  padding: 0;
  box-sizing: border-box;
}
.box {
  width: 300px;
  height: 200px;
  background-color: red;
  margin: 200px auto;
  position: relative;
}
.box .round1 {
  width: 10px;
  height: 10px;
  border-radius: 50%;
  border: 1px solid #fff;
  position: absolute;
  top: 50%;
  left: 50%;
  transform: translate(-50%, -50%);
  animation: move 1s infinite;
}
.box .round2 {
  width: 10px;
  height: 10px;
  border-radius: 50%;
  border: 1px solid #fff;
  position: absolute;
  top: 50%;
  left: 50%;
  transform: translate(-50%, -50%);
  animation: move 1s 0.5s infinite;
}
.box .round3 {
  width: 10px;
  height: 10px;
  border-radius: 50%;
  border: 1px solid #fff;
  position: absolute;
  top: 50%;
  left: 50%;
  transform: translate(-50%, -50%);
  animation: move 1s 1s infinite;
}
@keyframes move {
  to {
    transform: translate(-50%, -50%) scale(8);
    opacity: 0;
  }
}
